Outcomes of Laparoscopic Heller Myotomy for Achalasia: 22-Year Experience

J Gastrointest Surg. 2020 Jun;24(6):1411-1416. doi: 10.1007/s11605-020-04586-7. Epub 2020 Apr 16.

Abstract

Introduction: Laparoscopic Heller Myotomy is the most effective treatment of achalasia. We examined the durability of symptomatic relief, with and without fundoplication.

Methods: A single institution database between 1995 and 2017 was reviewed. Achalasia symptom severity was assessed by Eckardt scores (ES) obtained at 3-time points via patient questionnaire. Primary outcome was treatment success defined as ES of < 3.

Results: Completed surveys were returned by 130 patients (median follow-up of 6.6 years). A partial fundoplication was performed in 86%. At both 1-year and late follow-up, patients reported a significant improvement in ES compared to baseline (p < 0.05). Of those followed for ≥ 10 years (n = 44), 82% reported ES < 3 at 1-year (p < 0.001), and 78% at last follow-up (p < .001). Of patients who reported treatment success 1-year postoperatively (103/130), 85% continued to report symptomatic relief at last follow-up. Five-year cohort analysis did not show deterioration of dysphagia relief over time. The presence or absence of fundoplication had no impact on long-term outcome (p > 0.05).

Conclusions: LHM provides immediate and durable symptomatic relief, with very few patients requiring further therapeutic intervention. Fundoplication does not appear to influence the durability of symptom relief. Treatment success at 1-year is predictive of long-lasting symptomatic relief.

Keywords: Achalasia; Fundoplication; Laparoscopic Heller myotomy; Patient-reported outcomes.

MeSH terms

  • Deglutition Disorders* / surgery
  • Esophageal Achalasia* / surgery
  • Fundoplication
  • Heller Myotomy*
  • Humans
  • Laparoscopy*
  • Treatment Outcome