Targeted Radiotherapy of the Tumor Cavity after Surgical Resection of Aggressive Recurrent Brain Metastasis: A Case Report

Pavel Fadrus; Tomas Kazda; Petr Dvoracek; Petr Pospisil; Ludmila Hynkova; Jana Zitterbartova; Radana Dymackova; Ivana Kolouskova; Renata Belanova; Tomas Prochazka; Pavel Slampa

doi:10.1159/000506328

Targeted Radiotherapy of the Tumor Cavity after Surgical Resection of Aggressive Recurrent Brain Metastasis: A Case Report

Case Rep Oncol. 2020 Mar 19;13(1):233-238. doi: 10.1159/000506328. eCollection 2020 Jan-Apr.

Authors

Pavel Fadrus¹, Tomas Kazda^{2

3}, Petr Dvoracek², Petr Pospisil^{2

3}, Ludmila Hynkova^{2

3}, Jana Zitterbartova^{2

3}, Radana Dymackova^{2

3}, Ivana Kolouskova⁴, Renata Belanova^{4

5}, Tomas Prochazka^{2

3}, Pavel Slampa^{2

3}

Affiliations

¹ Department of Neurosurgery, University Hospital Brno and Faculty of Medicine, Masaryk University, Brno, Czechia.
² Department of Radiation Oncology, Masaryk Memorial Cancer Institute, Brno, Czechia.
³ Department of Radiation Oncology, Faculty of Medicine, Masaryk University, Brno, Czechia.
⁴ Faculty of Medicine, Masaryk University, Brno, Czechia.
⁵ Department of Radiology, Masaryk Memorial Cancer Institute, Brno, Czechia.

Abstract

Postoperative management of patients with brain metastases is controversial. Besides local control, cognitive function and quality of life are the most important outcomes of postoperative radiotherapy. In this case report, we introduce a patient with aggressive recurred solid metastasis treated with repeated surgery and an individual radiotherapy approach in order to highlight that close mutual collaboration leads to a clear benefit for our patients. The local targeted radiotherapy with 35 Gy in 10 fractions was performed with the volumetric modulated arc technique, leading to more than 2.5 years of local control and survival without any of the side effects usually attributed to whole brain radiotherapy.

Keywords: Brain metastases; Local control; Radiotherapy.

Publication types

Case Reports