Feasibility and acceptability of the multi-component P3-MumBubVax antenatal intervention to promote maternal and childhood vaccination: A pilot study

Jessica Kaufman; Katie Attwell; Jane Tuckerman; Jacinta O'Sullivan; Saad B Omer; Julie Leask; Annette Regan; Helen Marshall; Katherine J Lee; Tom Snelling; Kirsten Perrett; Kerrie Wiley; Michelle L Giles; Margie Danchin

doi:10.1016/j.vaccine.2020.04.010

Feasibility and acceptability of the multi-component P3-MumBubVax antenatal intervention to promote maternal and childhood vaccination: A pilot study

Vaccine. 2020 May 19;38(24):4024-4031. doi: 10.1016/j.vaccine.2020.04.010. Epub 2020 Apr 19.

Authors

Jessica Kaufman¹, Katie Attwell², Jane Tuckerman³, Jacinta O'Sullivan⁴, Saad B Omer⁵, Julie Leask⁶, Annette Regan⁷, Helen Marshall⁸, Katherine J Lee⁹, Tom Snelling¹⁰, Kirsten Perrett¹¹, Kerrie Wiley¹², Michelle L Giles¹³, Margie Danchin¹⁴

Affiliations

¹ Murdoch Children's Research Institute, 50 Flemington Road, Parkville, VIC 3052, Australia; Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, 50 Flemington Road, Parkville, VIC 3052, Australia. Electronic address: jess.kaufman@mcri.edu.au.
² Faculty of Arts, Business, Law and Education, School of Social Sciences, University of Western Australia, 35 Stirling Highway, Perth, WA 6009, Australia; Wesfarmers Centre of Vaccines & Infectious Diseases, Telethon Kids Institute, Perth Children's Hospital, 15 Hospital Avenue, Nedlands, WA 6009, Australia. Electronic address: katie.attwell@uwa.edu.au.
³ Murdoch Children's Research Institute, 50 Flemington Road, Parkville, VIC 3052, Australia; Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, 50 Flemington Road, Parkville, VIC 3052, Australia. Electronic address: jane.tuckerman@mcri.edu.au.
⁴ Murdoch Children's Research Institute, 50 Flemington Road, Parkville, VIC 3052, Australia. Electronic address: nickcind@bigpond.net.au.
⁵ Yale Institute for Global Health, Yale University, PO Box 208034, New Haven, CT 06520, United States. Electronic address: saad.omer@yale.edu.
⁶ University of Sydney Susan Wakil School of Nursing and Midwifery, 88 Mallett St, Camperdown, NSW 2050, Australia. Electronic address: julie.leask@sydney.edu.au.
⁷ Wesfarmers Centre of Vaccines & Infectious Diseases, Telethon Kids Institute, Perth Children's Hospital, 15 Hospital Avenue, Nedlands, WA 6009, Australia; School of Public Health, Texas A&M University, College Station, TX 77845, United States. Electronic address: a_regan@exchange.tamu.edu.
⁸ Robinson Research Institute and Adelaide Medical School, University of Adelaide, 55 King William St, North Adelaide, SA 5006, Australia; Women's and Children's Health Network, 72 King William Rd, North Adelaide, SA 5006, Australia. Electronic address: helen.marshall@adelaide.edu.au.
⁹ Murdoch Children's Research Institute, 50 Flemington Road, Parkville, VIC 3052, Australia; Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, 50 Flemington Road, Parkville, VIC 3052, Australia. Electronic address: katherine.lee@mcri.edu.au.
¹⁰ Wesfarmers Centre of Vaccines & Infectious Diseases, Telethon Kids Institute, Perth Children's Hospital, 15 Hospital Avenue, Nedlands, WA 6009, Australia; Perth Children's Hospital, 15 Hospital Avenue, Nedlands, WA 6009, Australia; School of Public Health, Curtin University, Kent Street, Bentley, WA 6102, Australia; Menzies School of Health Research and Charles Darwin University, PO Box 41096, Casuarina, NT 0811, Australia. Electronic address: Tom.Snelling@telethonkids.org.au.
¹¹ Murdoch Children's Research Institute, 50 Flemington Road, Parkville, VIC 3052, Australia; Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, 50 Flemington Road, Parkville, VIC 3052, Australia; Royal Children's Hospital, 50 Flemington Road, Parkville, VIC 3052, Australia. Electronic address: kirsten.perrett@mcri.edu.au.
¹² University of Sydney School of Public Health, A27 Fisher Rd, Camperdown, NSW 2006, Australia. Electronic address: kerrie.wiley@sydney.edu.au.
¹³ Department of Obstetrics and Gynaecology, Monash University, Clayton, VIC 3168, Australia. Electronic address: m.giles@alfred.org.au.
¹⁴ Murdoch Children's Research Institute, 50 Flemington Road, Parkville, VIC 3052, Australia; Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, 50 Flemington Road, Parkville, VIC 3052, Australia; Royal Children's Hospital, 50 Flemington Road, Parkville, VIC 3052, Australia. Electronic address: margie.danchin@rch.org.au.

PMID: 32321684
DOI: 10.1016/j.vaccine.2020.04.010

Abstract

Background: Pregnancy is a critical time for vaccine decision-making, but coverage remains suboptimal for maternal influenza (45-60%) and pertussis vaccination (65-80%) in Australia. The multi-component P3-MumBubVax intervention has been designed for Australian midwives to optimise antenatal vaccine discussions and improve maternal and childhood vaccine uptake. A pilot study was conducted to assess intervention feasibility and acceptability.

Methods: P3-MumBubVax includes components at three levels: 1. Practice ('vaccine champions'; stickers to prompt and record vaccine discussions/delivery); 2. Provider (website with vaccine communication training; learning exercise; fact sheets; links to child vaccination resources); 3. Parent (SMS reminders; website; fact sheets). Midwives and pregnant women 18-22 weeks gestation were recruited at the Royal Women's Hospital, Melbourne. Post-intervention online surveys assessed intervention feasibility, implementation, acceptability and impact on vaccine uptake.

Results: Twenty-five midwives and 62 pregnant women were recruited and 19/25 midwives completed training. Surveys were returned by 18/25 midwives and 56/62 women. 14/18 midwives reported using the sticker prompts, 10/18 reported using or referring to the website, and 11/18 reported using the fact sheets. 48/56 pregnant women (86%) reported discussing influenza and 46/56 (82%) discussed pertussis vaccines with their midwives. These conversations were reported to be short (1-3 min) for 48/56 women (87%). All midwives were satisfied with the intervention and 17/18 reported feeling more confident discussing vaccines following the intervention. Women were very satisfied with SMS content (50/56; 94%) and timing (49/55; 89%), and with their vaccine discussions in general (34/56; 63%). However, 16/54 (30%) wanted more discussion about childhood vaccines. Self-reported maternal vaccine uptake was 82% (45/55) and 93% (51/55) for influenza and pertussis (baseline 2017-2018: 43% influenza, 60% pertussis) and 96% (50/52) of infants were fully vaccinated at 12 weeks.

Discussion: The P3-MumBubVax intervention is feasible and acceptable in the Australian public antenatal setting. Further evaluation is required to determine effectiveness.

Keywords: Communication; Feasibility study; Health services; Implementation; Maternal immunisation; Midwifery; Vaccination.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Australia
Feasibility Studies
Female
Health Knowledge, Attitudes, Practice
Health Promotion / methods*
Humans
Infant
Influenza Vaccines / administration & dosage*
Influenza, Human* / prevention & control
Midwifery
Patient Education as Topic
Pilot Projects
Pregnancy
Prenatal Care*
Vaccination / statistics & numerical data*

Substances

Influenza Vaccines