Pulmonary Nocardiosis with Aspergillosis in a patient with COPD: A rare co-infection

Durga Shankar Meena; Deepak Kumar; Gopal Krishana Bohra; Mahendra Kumar Garg; Prakrati Yadav; Anuradha Sharma; Kumar S Abhishek; Pawan Garg; Jaya Pamnani

doi:10.1016/j.idcr.2020.e00766

Pulmonary Nocardiosis with Aspergillosis in a patient with COPD: A rare co-infection

IDCases. 2020 Apr 15:20:e00766. doi: 10.1016/j.idcr.2020.e00766. eCollection 2020.

Authors

Durga Shankar Meena¹, Deepak Kumar¹, Gopal Krishana Bohra¹, Mahendra Kumar Garg¹, Prakrati Yadav¹, Anuradha Sharma², Kumar S Abhishek², Pawan Garg³, Jaya Pamnani³

Affiliations

¹ Department of Medicine, All India Institute of Medical Sciences, Jodhpur, Rajasthan, 342005 India.
² Department of Microbiology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, 342005 India.
³ Department of Radiology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, 342005 India.

Abstract

Pulmonary Nocardiosis and invasive Aspergillosis are well documented in immunocompromised patients. The coexistence of both infections is a diagnostic rarity, especially in patients with underlying structural lung diseases. We describe this rare association in a 46-year-old female with a history of pulmonary tuberculosis and COPD. The diagnosis of pulmonary Nocardiosis is challenging due to non-specific clinical features, inherent ability to mimic malignancy, tuberculosis and difficulty in the cultivation of the organism. The treating physicians should aware of the rare occurrence of such co-infections in order to prevent misdiagnosis and prompt treatment.

Keywords: Aspergillosis; COPD; Nocardia; Old Tuberculosis.

Publication types

Case Reports