Heterogenous mutation spectrum and deregulated cellular pathways in aberrant plasma cells underline molecular pathology of light-chain amyloidosis

Affiliations

• ¹ Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
• ² Dpt. of Clinical studies, Faculty of Medicine, University of Ostrava, Ostrava, Czech Republic.
• ³ Institute of Molecular and Translational Medicine, Palacky University, Olomouc, Czech Republic.
• ⁴ Brno University of Technology, Centre of Excellence IT4Innovations, Brno, Czech Republic.
• ⁵ Institute of Biostatistics and Analyses, Masaryk University, Brno, Czech Republic.
• ⁶ Department of Biology and Ecology, Faculty of Science, University of Ostrava, Czech Republic.
• ⁷ Dept. of Hematology and Cancer Prevention, Medical University of Silesia in Katowice, Poland.
• ⁸ Department of Haematology, Oncology and Internal Diseases, Medical University of Warsaw, Poland.
• ⁹ Charles University Hospital Pilsen, Czech Republic.
• ¹⁰ Biosciences Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.
• ¹¹ IT4Innovations, VSB, Technical University of Ostrava, Ostrava, Czech Republic.
• ¹² Department of Internal Medicine, Hematology and Oncology, University Hospital Brno, Czech Republic.
• ¹³ Department of Haematology and Transfusiology, University Hospital Bratislava, Slovakia.
• ¹⁴ Dept. of Haematology and Stem Cell Transplantation, South Pest Central Hospital, Budapest, Hungary.
• ¹⁵ Department of Haematology, Medical University of Lodz, Copernicus Memorial Hospital, Łódź, Poland.
• ¹⁶ Dept. and Clinic of Haematology, Blood Neoplasms, Wroclaw Medical University, Poland.
• ¹⁷ Jagiellonian University Medical College, Cracow, Poland.
• ¹⁸ Silesian Hospital Opava, Opava, Czech Republic.
• ¹⁹ Dpt. of Medicine, Multiple Myeloma Research Perlmutter Cancer Center, NYU School of Medicine, USA.
• ²⁰ Department of Haematooncology, University Hospital Ostrava, Ostrava, Czech Republic.
• ²¹ RECETOX, Faculty of Science, Masaryk university in Brno, Brno, Czech Republic.