Ambulance dispatch calls attributable to influenza A and other common respiratory viruses in the Netherlands (2014-2016)

Influenza Other Respir Viruses. 2020 Jul;14(4):420-428. doi: 10.1111/irv.12731. Epub 2020 May 14.

Abstract

Background: Ambulance dispatches could be useful for syndromic surveillance of severe respiratory infections. We evaluated whether ambulance dispatch calls of highest urgency reflect the circulation of influenza A virus, influenza B virus, respiratory syncytial virus (RSV), rhinovirus, adenovirus, coronavirus, parainfluenzavirus and human metapneumovirus (hMPV).

Methods: We analysed calls from four ambulance call centres serving 25% of the population in the Netherlands (2014-2016). The chief symptom and urgency level is recorded during triage; we restricted our analysis to calls with the highest urgency and identified those compatible with a respiratory syndrome. We modelled the relation between respiratory syndrome calls (RSC) and respiratory virus trends using binomial regression with identity link function.

Results: We included 211 739 calls, of which 15 385 (7.3%) were RSC. Proportion of RSC showed periodicity with winter peaks and smaller interseasonal increases. Overall, 15% of RSC were attributable to respiratory viruses (20% in out-of-office hour calls). There was large variation by age group: in <15 years, only RSV was associated and explained 11% of RSC; in 15-64 years, only influenza A (explained 3% of RSC); and in ≥65 years adenovirus explained 9% of RSC, distributed throughout the year, and hMPV (4%) and influenza A (1%) mainly during the winter peaks. Additionally, rhinovirus was associated with total RSC.

Conclusion: High urgency ambulance dispatches reflect the burden of different respiratory viruses and might be useful to monitor the respiratory season overall. Influenza plays a smaller role than other viruses: RSV is important in children while adenovirus and hMPV are the biggest contributors to emergency calls in the elderly.

Keywords: adenovirus; ambulance; coronavirus; influenza; respiratory syncytial virus; rhinovirus.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Ambulances*
  • Child
  • Emergency Medical Dispatch / statistics & numerical data*
  • Female
  • Humans
  • Influenza, Human / epidemiology*
  • Male
  • Middle Aged
  • Netherlands / epidemiology
  • Respiratory Tract Infections / epidemiology
  • Respiratory Tract Infections / virology*
  • Seasons
  • Young Adult