Forensic Features and Population Genetic Structure of Dong, Yi, Han, and Chuanqing Human Populations in Southwest China Inferred From Insertion/Deletion Markers

Yubo Liu; Han Zhang; Guanglin He; Zheng Ren; Hongling Zhang; Qiyan Wang; Jingyan Ji; Meiqing Yang; Jianxin Guo; Xiaomin Yang; Jin Sun; Jinxing Ba; Dan Peng; Rong Hu; Lan-Hai Wei; Chuan-Chao Wang; Jiang Huang

doi:10.3389/fgene.2020.00360

Forensic Features and Population Genetic Structure of Dong, Yi, Han, and Chuanqing Human Populations in Southwest China Inferred From Insertion/Deletion Markers

Front Genet. 2020 Apr 30:11:360. doi: 10.3389/fgene.2020.00360. eCollection 2020.

Authors

Yubo Liu¹, Han Zhang¹, Guanglin He^{2

3}, Zheng Ren¹, Hongling Zhang¹, Qiyan Wang¹, Jingyan Ji¹, Meiqing Yang¹, Jianxin Guo², Xiaomin Yang², Jin Sun², Jinxing Ba², Dan Peng⁴, Rong Hu², Lan-Hai Wei², Chuan-Chao Wang², Jiang Huang¹

Affiliations

¹ Department of Forensic Medicine, Guizhou Medical University, Guiyang, China.
² Department of Anthropology and Ethnology, Institute of Anthropology, National Institute for Data Science in Health and Medicine, and School of Life Sciences, Xiamen University, Xiamen, China.
³ Institute of Forensic Medicine, West China School of Basic Science and Forensic Medicine, Sichuan University, Chengdu, China.
⁴ Faculty of Forensic Medicine, Zhongshan School of Medicine, Sun Yat-sen University, Guangzhou, China.

Abstract

Guizhou province in southwest China has abundant genetic and cultural diversities, but the forensic features and genetic structure of Guizhou populations remain poorly understood due to the sparse sampling of present-day populations. Here, we present 30 insertion/deletion polymorphisms (InDels) data of 591 human individuals collected from four populations, Dong, Yi, Han, and Chuanqing residing in Guizhou. We calculated the forensic parameters of 30 InDel loci and found that this panel meets the efficiency of forensic personal identification based on the high combined power of discrimination, but it could only be used as a complementary tool in the parentage testing because of the lower combined probability of exclusion values. The studied populations are genetically closer related to geographically adjacent or linguistically related populations in southern China, such as the Tai-Kadai and Hmong-Mien speaking groups. The unrecognized ethnic Chuanqing people show an additional genetic affinity with Han Chinese, highlighting the role of possible military immigrations in their origin.

Keywords: Chuanqing human population; Dong human population; Guizhou human population; Han human population; Investigator® DIPplex Kit; Yi human population; forensic genetics; population structure.