Natural History, Clinical, and Surgical Management of Cavernous Malformations

Methods Mol Biol. 2020:2152:35-46. doi: 10.1007/978-1-0716-0640-7_3.

Abstract

We describe Natural history, clinical and surgical management of cavernous malformation of the brain and spinal cord. Decision-making for treatment of cavernous malformations cannot ignore their natural history and risk of bleeding, which is different depending on the location. Surgical morbidity also depends on the position of the lesion. We performed a review of hemorrhage risk and clinical assessment of superficial and deep supratentorial, brainstem and intramedullary cavernous malformations.

Keywords: Angioma; Cavernous malformations; Hemorrhage risk; Microsurgical management; Natural history.

Publication types

  • Review

MeSH terms

  • Comorbidity
  • Diagnosis, Differential
  • Disease Management
  • Disease Susceptibility
  • Female
  • Hemangioma, Cavernous, Central Nervous System / diagnosis*
  • Hemangioma, Cavernous, Central Nervous System / epidemiology
  • Hemangioma, Cavernous, Central Nervous System / etiology
  • Hemangioma, Cavernous, Central Nervous System / surgery*
  • Hemorrhage / etiology
  • Hemorrhage / prevention & control
  • Humans
  • Male
  • Phenotype
  • Symptom Assessment
  • Treatment Outcome