Autoantigen TRIM21/Ro52 is expressed on the surface of antigen-presenting cells and its enhanced expression in Sjögren's syndrome is associated with B cell hyperactivity and type I interferon activity

RMD Open. 2020 Jun;6(2):e001184. doi: 10.1136/rmdopen-2020-001184.

Maarten R Hillen^#^{1

2}, Katia Urso^#³, Emma Koppe³, Ana Pinheiro Lopes^{1

2}, Sofie L M Blokland^{1

2}, Aridaman Pandit^{1

2}, Tom Slocombe³, André van Maurik⁴, Joel A G van Roon^{5

2}, Timothy R D J Radstake^{1

3}

¹ Centre for Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
² Department of Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
³ GSK Immunology Network and Adaptive Immunity Research Unit, GlaxoSmithKline, Stevenage, UK.
⁴ Clinical Pharmacology and Experimental Medicine, GlaxoSmithKline, Stevenage, UK.
⁵ Centre for Translational Immunology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands j.vanroon@umcutrecht.nl.

^# Contributed equally.

No abstract available

Keywords: Autoimmunity; Inflammation; Sjøgren’s Syndrome.

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