68Ga-DOTATATE and 18F-FDG PET/CT for the Management of Esthesioneuroblastoma of the Sphenoclival Region

Clin Nucl Med. 2020 Aug;45(8):e363-e364. doi: 10.1097/RLU.0000000000003133.

Abstract

We present a 48-year-old woman with an olfactory neuroblastoma who was referred for accurate staging using PET/CT. The Ga-DOTATATE PET/CT showed a 51 × 32-mm mass with an SUVmax of 7.59 in the sphenoidal sinuses, whereas radiotracer uptake on F-FDG PET/CT was similar to that of brain tissue. Ga-DOTATATE PET/CT might be especially useful in regions with difficult tumor visualization resulting from high background, such as brain tissue. The results of this case may suggest that somatostatin receptor imaging in patients with esthesioneuroblastoma may facilitate the potential application of radiotheranostic agents for the treatment of this aggressive subtype of tumors.

Publication types

  • Case Reports

MeSH terms

  • Esthesioneuroblastoma, Olfactory / diagnostic imaging*
  • Esthesioneuroblastoma, Olfactory / metabolism
  • Female
  • Fluorodeoxyglucose F18*
  • Humans
  • Middle Aged
  • Nasal Cavity / diagnostic imaging*
  • Nose Neoplasms / diagnostic imaging*
  • Nose Neoplasms / metabolism
  • Organometallic Compounds*
  • Positron Emission Tomography Computed Tomography*
  • Receptors, Somatostatin / metabolism

Substances

  • Organometallic Compounds
  • Receptors, Somatostatin
  • Fluorodeoxyglucose F18
  • gallium Ga 68 dotatate