Neurosarcoidosis: Analysis of a series of 20 patients

Abstract

Introduction: Neurosarcoidosis is a rare complication of sarcoidosis. There are small series on the condition and very few from Spain. We conducted a retrospective study of neurosarcoidosis in Virgen de la Victoria Hospital over the last 10 years.

Patients and method: the medical records of patients diagnosed with sarcoidosis in our setting in the last 10 years were reviewed.

Results: One hundred twenty patients with sarcoidosis, 20 patients with probable neurosarcoidosis: 30% at the beginning of the illness, 55% later, 15% had isolated neurosarcoidosis. Forty percent had polyneuropathy, 15% cranial neuropathy, 15% myopathy, 10% hemispheric symptoms. OTHERS: headache, myelitis, seizures, confusional syndrome. They were treated with steroids, some of them with immunosuppressive treatment. Seventy-two percent improved or were stabilized. Therefore, neurosarcoidosis prevalence in our hospital was 11%, similar to other published series, with similar features, but polyneuropathy was more frequent. Early diagnosis is very important as prognosis is favourable with treatment.

Keywords: Cohort; Estudio retrospectivo; Neurosarcoidosis; Prognosis; Pronóstico; Retrospective study; Sarcoidosis; Serie; Tratamiento; Treatment.