Elevated levels of interleukin 2 receptor in sera of patients with atopic dermatitis and psoriasis

Br J Dermatol. 1988 Dec;119(6):707-10. doi: 10.1111/j.1365-2133.1988.tb03491.x.

Abstract

Elevated levels of serum interleukin 2 receptor (IL2R) represent an early measure of T cell activation. The concentration of IL2R was measured in the sera of patients with atopic dermatitis (n = 58) or psoriasis, without psoriatic arthritis, (n = 26), who had moderate to severe disease activity, and in non-atopic healthy controls (n = 37) by an ELISA technique. Serum IL2R levels were found to be significantly elevated in both disease groups compared with the controls. The increase in serum IL2R may be due to T cell activation in the dermis.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Dermatitis, Atopic / immunology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Psoriasis / immunology*
  • Receptors, Interleukin-2 / analysis*

Substances

  • Receptors, Interleukin-2