Congenital Fusion of Dens to T3 Vertebra in Klippel-Feil Syndrome

World Neurosurg. 2020 Nov:143:18-22. doi: 10.1016/j.wneu.2020.06.232. Epub 2020 Jul 9.

Abstract

Background: Patients with Klippel-Feil syndrome may present with neurologic complaints such as neck pain, radiculopathy and gait instability. Here we describe surgical management of a patient with congenital fusion of the occipital-cervical region and also block circumferential fusion of dens to T3 with spinal cord compression. This report is the first of its kind with such extensive fusion.

Case description: Our patient was a 56 year-old female, who presented with neck pain and tingling in all extremities. On exam, she had a short neck, prominent jaw with extremely limited range of motion in neck and features of myelopathy. CT showed fusion of the dens to T3 vertebrae. Patient underwent sub-occipital craniectomy, C1 laminectomy and Occiput to T5 posterior fixation and fusion with neurologic improvement.

Conclusion: This is the first reported case of Klippel-Feil syndrome with fusion of all cervical vertebrae down to T3. We recommend surgery for advanced cases of myelopathy or radiculopathy due to stenosis and spinal instability.

Keywords: Cervical myelopathy; Congenital fusion; Fused spinal vertebrae; Klippel-Feil syndrome; Occipital-cervical fusion; Posterior cervical fusion.

Publication types

  • Case Reports

MeSH terms

  • Atlanto-Occipital Joint / diagnostic imaging
  • Atlanto-Occipital Joint / surgery
  • Cervical Vertebrae / abnormalities
  • Cervical Vertebrae / diagnostic imaging*
  • Cervical Vertebrae / surgery
  • Craniotomy
  • Decompression, Surgical
  • Female
  • Humans
  • Joint Instability / diagnostic imaging
  • Joint Instability / surgery
  • Klippel-Feil Syndrome / complications
  • Klippel-Feil Syndrome / diagnostic imaging*
  • Klippel-Feil Syndrome / physiopathology
  • Klippel-Feil Syndrome / surgery
  • Laminectomy
  • Magnetic Resonance Imaging
  • Middle Aged
  • Neurosurgical Procedures
  • Occipital Bone / abnormalities
  • Occipital Bone / diagnostic imaging
  • Occipital Bone / surgery
  • Odontoid Process / abnormalities
  • Odontoid Process / diagnostic imaging
  • Odontoid Process / surgery
  • Spinal Fusion
  • Spinal Stenosis / diagnostic imaging*
  • Spinal Stenosis / etiology
  • Spinal Stenosis / physiopathology
  • Spinal Stenosis / surgery
  • Thoracic Vertebrae / abnormalities
  • Thoracic Vertebrae / diagnostic imaging*
  • Thoracic Vertebrae / surgery
  • Tomography, X-Ray Computed