Uncommon cause of fever in a child with steroid-dependent nephrotic syndrome

Sidharth Kumar Sethi; Shyam Bansal; Ronith Chakraborty; Rahul Jain; Nikita Wadhwani; Rupesh Raina

doi:10.5414/CNCS110062

Uncommon cause of fever in a child with steroid-dependent nephrotic syndrome

Clin Nephrol Case Stud. 2020 Jul 7:8:49-52. doi: 10.5414/CNCS110062. eCollection 2020.

Authors

Sidharth Kumar Sethi¹, Shyam Bansal¹, Ronith Chakraborty², Rahul Jain², Nikita Wadhwani¹, Rupesh Raina^{2

3}

Affiliations

¹ Kidney Institute, Medanta, The Medicity Hospital, Gurgaon, Haryana, India, and.
² Akron General Medical Center, and.
³ Akron Children's Hospital, Akron, OH, USA.

Abstract

Background: Children with nephrotic syndrome are vulnerable to developing infections due to a state of relative immunodeficiency, malnourishment, and use of immunosuppression. Case characteristics: We herein report the case of a 3-year-old child with steroid-dependent nephrotic syndrome who presented to us with fever of unknown origin.

Observation: The child was found to have an atypical mixed infection with mycoplasma and cytomegalovirus.

Outcome: The infection completely resolved with appropriate treatment and lowering of immunosuppression. Message: Persistently febrile pediatric patients, especially in the setting of recent immunosuppression and absence of otherwise-identified infectious pathogens, should be screened for atypical mixed infections.

Keywords: CMV disease; Mycoplasma pneumoniae; fever of unknown origin; mixed opportunistic infection; steroid-dependent nephrotic syndrome.

Publication types

Case Reports