The history behind the mosaic of the Americas

Curr Opin Genet Dev. 2020 Jun:62:72-77. doi: 10.1016/j.gde.2020.06.007. Epub 2020 Jul 10.

Abstract

Focusing on literature published in 2018-2020, we review inferences about: (i) how ancient DNA is contributing to clarify the peopling of the Americas and the dispersal of its first inhabitants, (ii) how the interplay between environmental diversity and culture has influenced the genetic structure and adaptation of Andean and Amazon populations, (iii) how genetics has contributed to our understanding of the Pre-Columbian Tupi expansion in Eastern South America, (iv) the subcontinental origins and dynamics of Post-Columbian admixture in the Americas, and finally, (v) episodes of adaptive natural selection in the American continent, particularly in the high altitudes of the Andes.

Publication types

  • Historical Article
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Americas
  • Colombia
  • DNA, Ancient / analysis*
  • Genetic Variation*
  • Genetics, Population*
  • Genome, Human*
  • Haplotypes
  • History, Ancient
  • Human Migration / history*
  • Humans
  • Mosaicism*
  • Selection, Genetic*

Substances

  • DNA, Ancient