Deciphering the Novel Role of AtMIN7 in Cuticle Formation and Defense against the Bacterial Pathogen Infection

Int J Mol Sci. 2020 Aug 3;21(15):5547. doi: 10.3390/ijms21155547.

Abstract

The cuticle is the outermost layer of plant aerial tissue that interacts with the environment and protects plants against water loss and various biotic and abiotic stresses. ADP ribosylation factor guanine nucleotide exchange factor proteins (ARF-GEFs) are key components of the vesicle trafficking system. Our study discovers that AtMIN7, an Arabidopsis ARF-GEF, is critical for cuticle formation and related leaf surface defense against the bacterial pathogen Pseudomonas syringae pathovar tomato (Pto). Our transmission electron microscopy and scanning electron microscopy studies indicate that the atmin7 mutant leaves have a thinner cuticular layer, defective stomata structure, and impaired cuticle ledge of stomata compared to the leaves of wild type plants. GC-MS analysis further revealed that the amount of cutin monomers was significantly reduced in atmin7 mutant plants. Furthermore, the exogenous application of either of three plant hormones-salicylic acid, jasmonic acid, or abscisic acid-enhanced the cuticle formation in atmin7 mutant leaves and the related defense responses to the bacterial Pto infection. Thus, transport of cutin-related components by AtMIN7 may contribute to its impact on cuticle formation and related defense function.

Keywords: cutin; plant cuticle; plant defense; plant hormones; transport; vesicle trafficking.

MeSH terms

  • Abscisic Acid / metabolism
  • Arabidopsis / genetics*
  • Arabidopsis / growth & development
  • Arabidopsis / microbiology
  • Arabidopsis Proteins / genetics*
  • Bacterial Infections / genetics*
  • Bacterial Infections / microbiology
  • Disease Resistance
  • Gene Expression Regulation, Plant / genetics
  • Guanine Nucleotide Exchange Factors / genetics*
  • Membrane Lipids / genetics
  • Phenotype
  • Plant Diseases / genetics*
  • Plant Diseases / microbiology
  • Plant Epidermis / genetics
  • Plant Epidermis / growth & development
  • Plant Epidermis / microbiology
  • Plant Leaves / genetics
  • Plant Leaves / growth & development
  • Plant Leaves / metabolism
  • Pseudomonas syringae / genetics
  • Pseudomonas syringae / pathogenicity
  • Solanum lycopersicum / genetics
  • Solanum lycopersicum / growth & development
  • Solanum lycopersicum / microbiology
  • Stress, Physiological / genetics
  • Waxes / chemistry

Substances

  • Arabidopsis Proteins
  • At3g43300 protein, Arabidopsis
  • Guanine Nucleotide Exchange Factors
  • Membrane Lipids
  • Waxes
  • cutin
  • Abscisic Acid