Use of a Standardized Dalbavancin Approach to Facilitate Earlier Hospital Discharge for Vulnerable Patients Receiving Prolonged Inpatient Antibiotic Therapy

Axel A Vazquez Deida; Katherine C Shihadeh; Candice R Preslaski; Heather L Young; David L Wyles; Timothy C Jenkins

doi:10.1093/ofid/ofaa293

Use of a Standardized Dalbavancin Approach to Facilitate Earlier Hospital Discharge for Vulnerable Patients Receiving Prolonged Inpatient Antibiotic Therapy

Open Forum Infect Dis. 2020 Jul 13;7(8):ofaa293. doi: 10.1093/ofid/ofaa293. eCollection 2020 Aug.

Authors

Axel A Vazquez Deida¹, Katherine C Shihadeh¹, Candice R Preslaski¹, Heather L Young^{2

3}, David L Wyles^{2

3}, Timothy C Jenkins^{2

3}

Affiliations

¹ Pharmacy Department, Denver Health Medical Center, Denver, Colorado, USA.
² Division of Infectious Diseases, Department of Medicine, Denver Health Medical Center, Denver, Colorado, USA.
³ Division of Infectious Diseases, Department of Medicine, University of Colorado School of Medicine, Aurora, Colorado, USA.

Abstract

Twenty-seven patients receiving prolonged inpatient antibiotic therapy for a serious bacterial infection received a single dose of dalbavancin 7-10 days before the planned end date to facilitate earlier hospital discharge. Eighty-one percent met criteria for clinical success, 7% experienced a potential adverse event, and 182 hospital days were averted.

Keywords: Staphylococcus aureus; dalbavancin; persons experiencing homelessness; persons who use injection drugs; substance use disorder.