Magnetic covalent organic framework as a solid-phase extraction absorbent for sensitive determination of trace organophosphorus pesticides in fatty milk

Xiang-Ping Lin; Xin-Quan Wang; Jiao Wang; Yu-Wei Yuan; Shan-Shan Di; Zhi-Wei Wang; Hao Xu; Hui-Yu Zhao; Chang-Shan Zhao; Wei Ding; Pei-Pei Qi

doi:10.1016/j.chroma.2020.461387

Magnetic covalent organic framework as a solid-phase extraction absorbent for sensitive determination of trace organophosphorus pesticides in fatty milk

J Chromatogr A. 2020 Sep 13:1627:461387. doi: 10.1016/j.chroma.2020.461387. Epub 2020 Jul 3.

Authors

Xiang-Ping Lin¹, Xin-Quan Wang², Jiao Wang³, Yu-Wei Yuan⁴, Shan-Shan Di⁵, Zhi-Wei Wang², Hao Xu⁵, Hui-Yu Zhao⁵, Chang-Shan Zhao⁶, Wei Ding⁷, Pei-Pei Qi⁸

Affiliations

¹ State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Institute of Quality and Standard of Agro-products, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, P. R. China; College of Agriculture, Northeast Agricultural University, Harbin, 150030, P. R. China.
² State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Institute of Quality and Standard of Agro-products, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, P. R. China; Key Laboratory of Detection for Pesticide Residues and Control of Zhejiang, Hangzhou 310021, P. R. China; Agricultural Ministry Key Laboratory for Pesticide Residue Detection, Hangzhou 310021, P. R. China.
³ State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Institute of Quality and Standard of Agro-products, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, P. R. China.
⁴ State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Institute of Quality and Standard of Agro-products, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, P. R. China; Key Laboratory of Detection for Pesticide Residues and Control of Zhejiang, Hangzhou 310021, P. R. China.
⁵ State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Institute of Quality and Standard of Agro-products, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, P. R. China; Agricultural Ministry Key Laboratory for Pesticide Residue Detection, Hangzhou 310021, P. R. China.
⁶ College of Agriculture, Northeast Agricultural University, Harbin, 150030, P. R. China.
⁷ College of Agriculture, Northeast Agricultural University, Harbin, 150030, P. R. China. Electronic address: dingwei@neau.edu.cn.
⁸ State Key Laboratory for Managing Biotic and Chemical Threats to the Quality and Safety of Agro-products, Institute of Quality and Standard of Agro-products, Zhejiang Academy of Agricultural Sciences, Hangzhou 310021, P. R. China; Key Laboratory of Detection for Pesticide Residues and Control of Zhejiang, Hangzhou 310021, P. R. China; Agricultural Ministry Key Laboratory for Pesticide Residue Detection, Hangzhou 310021, P. R. China. Electronic address: qipeipei@zaas.ac.cn.

PMID: 32823095
DOI: 10.1016/j.chroma.2020.461387

Abstract

A simple and efficient magnetic solid-phase extraction (MSPE) method was established with magnetic covalent organic framework (COF) as adsorbent to enrich organophosphorus pesticides from fatty milk samples, followed by the sensitive determination via LC-MS/MS. The key parameters influencing the MSPE efficiency were comprehensively investigated to afford an optimized procedure. All the target analytes could be captured directly by magnetic COF from milk without protein precipitation, making the pretreatment rapid and convenient. Systematic method validation demonstrated its satisfactory linearity, recoveries (80.0-105 %), and precision (RSDs <12.3 %). The method limits of quantification were 0.2-0.5 μg L^-1. A comparison experiment to the reported solid-phase extraction fully verified the present MSPE more rapid, accurate, and environment-friendly. Furthermore, FT-IR and XPS analysis were performed to reveal the adsorption mechanisms of magnetic COF to organophosphorus pesticides, which could offer guidance on the rational design of COF adsorbent for various target analytes.

Keywords: Adsorbent; Magnetic covalent organic framework; Magnetic solid-phase extraction; Milk; Organophosphorus pesticides.

MeSH terms

Acetonitriles / analysis
Adsorption
Animals
Limit of Detection
Magnetic Phenomena*
Metal-Organic Frameworks / chemistry*
Milk / chemistry*
Organophosphorus Compounds / analysis*
Pesticides / analysis*
Photoelectron Spectroscopy
Reference Standards
Reproducibility of Results
Solid Phase Extraction / methods*
Solvents / chemistry
Spectroscopy, Fourier Transform Infrared

Substances

Acetonitriles
Metal-Organic Frameworks
Organophosphorus Compounds
Pesticides
Solvents
acetonitrile