Efflux Pump Antibiotic Binding Site Mutations Are Associated with Azithromycin Nonsusceptibility in Clinical Neisseria gonorrhoeae Isolates

mBio. 2020 Aug 25;11(4):e01509-20. doi: 10.1128/mBio.01509-20.

Authors

Kevin C Ma^#¹, Tatum D Mortimer^#¹, Yonatan H Grad^{2

3}

Affiliations

¹ Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA.
² Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, Massachusetts, USA ygrad@hsph.harvard.edu.
³ Division of Infectious Diseases, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.

^# Contributed equally.

No abstract available

Publication types

Letter
Comment

MeSH terms

Anti-Bacterial Agents
Azithromycin
Binding Sites
Cryoelectron Microscopy
Drug Resistance, Bacterial / drug effects
Gonorrhea*
Humans
Mutation / drug effects
Neisseria gonorrhoeae / drug effects*

Substances

Anti-Bacterial Agents
Azithromycin

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