Blood loss and transfusion rate in patients undergoing two-stage exchange in infected total knee arthroplasty

J Biol Regul Homeost Agents. 2020 May-Jun;34(3 Suppl. 2):1-5. ADVANCES IN MUSCULOSKELETAL DISEASES AND INFECTIONS - SOTIMI 2019.

Abstract

Two-stage exchange in infected total knee arthroplasty is a reliable technique, but it has a high rate of blood loss. The study aims to compare the pre-operative and post-operative haemoglobin levels, the rate of transfusion, and the blood loss in two-stage exchange. From July 2018 to July 2019, eighteen patients underwent two-stage exchange of their infected total knee arthroplasty. Local and systemic tranexamic acid was administered in both surgical stages. Calculated blood loss was 2246 mL (range 1528 - 2850) in the first stage and 2388 mL (1873 - 2829) during reimplantation, respectively. The corresponding transfusion rate was 55 % and 67%, respectively. With the numbers available, these differences were not significant. In conclusion, this study shows that the blood loss and transfusion rate are similar during the two stages of exchange knee arthroplasty for infection.

Keywords: blood loss; prosthetic joint infection; total knee arthroplasty; transfusion; two-stage.

Publication types

  • Review

MeSH terms

  • Antifibrinolytic Agents
  • Arthroplasty, Replacement, Knee* / adverse effects
  • Blood Loss, Surgical
  • Blood Transfusion*
  • Humans
  • Tranexamic Acid

Substances

  • Antifibrinolytic Agents
  • Tranexamic Acid