Questions concerning the proximal origin of SARS-CoV-2

Murat Seyran; Damiano Pizzol; Parise Adadi; Tarek M A El-Aziz; Sk Sarif Hassan; Antonio Soares; Ramesh Kandimalla; Kenneth Lundstrom; Murtaza Tambuwala; Alaa A A Aljabali; Amos Lal; Gajendra K Azad; Pabitra P Choudhury; Vladimir N Uversky; Samendra P Sherchan; Bruce D Uhal; Nima Rezaei; Adam M Brufsky

doi:10.1002/jmv.26478

Questions concerning the proximal origin of SARS-CoV-2

J Med Virol. 2021 Mar;93(3):1204-1206. doi: 10.1002/jmv.26478. Epub 2020 Dec 30.

Authors

Murat Seyran^{1

2}, Damiano Pizzol³, Parise Adadi⁴, Tarek M A El-Aziz^{5

6}, Sk Sarif Hassan⁷, Antonio Soares⁵, Ramesh Kandimalla^{8

9}, Kenneth Lundstrom¹⁰, Murtaza Tambuwala¹¹, Alaa A A Aljabali¹², Amos Lal¹³, Gajendra K Azad¹⁴, Pabitra P Choudhury¹⁵, Vladimir N Uversky¹⁶, Samendra P Sherchan¹⁷, Bruce D Uhal¹⁸, Nima Rezaei^{19

20}, Adam M Brufsky²¹

Affiliations

¹ Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Doctoral Studies in Natural and Technical Sciences (SPL 44)xs, University of Vienna, Vienna, Austria.
² Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Vienna, Austria.
³ Italian Agency for Development Cooperation - Khartoum, Al Amarat, Sudan.
⁴ Department of Food Science, University of Otago, Dunedin, New Zealand.
⁵ Department of Cellular and Integrative Physiology, University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
⁶ Department of Zoology, Faculty of Science, Minia University, El-Minia, Egypt.
⁷ Department of Mathematics, Pingla Thana Mahavidyalaya, Maligram, West Bengal, India.
⁸ CSIR-Indian Institute of Chemical Technology, Hyderabad, Telangana, India.
⁹ Kakatiya Medical College/MGM-Hospital, DME/TSPSC, Hyderabad, Warangal, Telangana, India.
¹⁰ PanTherapeutics, Lutry, Switzerland.
¹¹ School of Pharmacy and Pharmaceutical Science, Ulster University, Coleraine, Northern Ireland, UK.
¹² Department of Pharmaceutical Sciences, Faculty of Pharmacy, Yarmouk University, Irbid, Jordan.
¹³ Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota, USA.
¹⁴ Department of Zoology, Patna University, Patna, India.
¹⁵ Applied Statistics Unit Indian Statistical Institute, Kolkata, West Bengal, India.
¹⁶ Department of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.
¹⁷ Department of Environmental Health Sciences, Tulane University, New Orleans, Louisiana, USA.
¹⁸ Department of Physiology, Michigan State University, East Lansing, Michigan, USA.
¹⁹ Center for Immunodeficiencies, Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran.
²⁰ Network of Immunity in Infection, Malignancy and Autoimmunity (NIIMA), Universal Scientific Education and Research Network (USERN), Tehran, Iran.
²¹ Department of Medicine, Division of Hematology/Oncology, UPMC Hillman Cancer Center, Pittsburgh, Pennsylvania, USA.

No abstract available

Keywords: coronavirus; fusion protein; genetic variability; mutation.

Publication types

Letter

MeSH terms

Animals
COVID-19 / epidemiology
COVID-19 / virology*
Coronavirus / chemistry
Coronavirus / genetics
Host Adaptation
Humans
Mutation
Protein Binding
Protein Domains
RNA, Viral / genetics
Recombination, Genetic
SARS-CoV-2 / chemistry*
SARS-CoV-2 / genetics*
SARS-CoV-2 / growth & development
SARS-CoV-2 / physiology
Spike Glycoprotein, Coronavirus / chemistry*
Spike Glycoprotein, Coronavirus / genetics
Viral Tropism

Substances

RNA, Viral
Spike Glycoprotein, Coronavirus
spike protein, SARS-CoV-2