Human stem cell-derived astrocytes exhibit region-specific heterogeneity in their secretory profiles
Brain
.
2020 Oct 1;143(10):e85.
doi: 10.1093/brain/awaa258.
Authors
Benjamin E Clarke
1
2
,
Doaa M Taha
1
2
3
,
Oliver J Ziff
1
2
,
Aftab Alam
4
,
Eric P Thelin
4
5
,
Núria Marcó García
4
,
Adel Helmy
4
,
Rickie Patani
1
2
Affiliations
1
Department of Neuromuscular Diseases, Queen Square Institute of Neurology, University College London, London, UK.
2
The Francis Crick Institute, London NW1 1AT, UK.
3
Department of Zoology, Faculty of Science, Alexandria University, Alexandria 21511, Egypt.
4
Division of Neurosurgery and Wolfson Brain Imaging Centre, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
5
Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden.
PMID:
32895697
PMCID:
PMC7586081
DOI:
10.1093/brain/awaa258
No abstract available
Publication types
Letter
Research Support, Non-U.S. Gov't
MeSH terms
Astrocytes / metabolism*
Cell Differentiation / physiology*
Humans
Induced Pluripotent Stem Cells / metabolism*
Neural Stem Cells / metabolism*
Grants and funding
MR/R005036/1/MRC_/Medical Research Council/United Kingdom
FC010110/WT_/Wellcome Trust/United Kingdom
MR/S006591/1/MRC_/Medical Research Council/United Kingdom
G0802251/MRC_/Medical Research Council/United Kingdom
FC010110/MRC_/Medical Research Council/United Kingdom
WT_/Wellcome Trust/United Kingdom
FC010110/CRUK_/Cancer Research UK/United Kingdom