Pulmonary complications of transfusion: Changes, challenges, and future directions

Sharran Grey; Paula Bolton-Maggs

doi:10.1111/tme.12709

Pulmonary complications of transfusion: Changes, challenges, and future directions

Transfus Med. 2020 Dec;30(6):442-449. doi: 10.1111/tme.12709. Epub 2020 Sep 13.

Authors

Sharran Grey^{1

2}, Paula Bolton-Maggs^{2

3}

Affiliations

¹ Lancashire Haematology Centre, Blackpool Teaching Hospitals NHS Foundation Trust, North Lancashire, UK.
² Serious Hazards of Transfusion, Manchester Blood Centre, Manchester, UK.
³ Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.

PMID: 32924216
DOI: 10.1111/tme.12709

Abstract

The pulmonary complications of transfusion (TACO, TRALI and TAD) are the leading cause of transfusion-related mortality and major morbidity. Advance in this area is essential in improving transfusion safety. This review describes the drivers for change in haemovigilance practice, the influence of recent key publications and future directions.

Keywords: ARDS; TACO; TAD; TRALI; haemovigilance; pulmonary complications; transfusion reaction.

Publication types

Review

MeSH terms

Blood Safety*
Blood Transfusion*
Humans
Transfusion-Related Acute Lung Injury* / blood
Transfusion-Related Acute Lung Injury* / prevention & control