In search of anti-aging interventions with differential effects on normal and cancer cells, we show that cycles of a fasting-mimicking diet plus pharmacological doses of vitamin C can be effective in targeting KRAS-mutant cancers. This approach represents a promising strategy able to protect the organism while killing cancer cells.
Keywords: Fasting-mimicking diet; KRAS-mutant cancers; iron metabolism; vitamin C.
© 2020 The Author(s). Published with license by Taylor & Francis Group, LLC.