The Complete Genome Sequence of Xanthomonas theicola, the Causal Agent of Canker on Tea Plants, Reveals Novel Secretion Systems in Clade-1 Xanthomonads

Phytopathology. 2021 Apr;111(4):611-616. doi: 10.1094/PHYTO-07-20-0273-SC. Epub 2021 Feb 26.

Abstract

Xanthomonas theicola is the causal agent of bacterial canker on tea plants. There is no complete genome sequence available for X. theicola, a close relative of the species X. translucens and X. hyacinthi, thus limiting basic research for this group of pathogens. Here, we release a high-quality complete genome sequence for the X. theicola type strain, CFBP 4691T. Single-molecule real-time sequencing with a mean coverage of 264× revealed two contigs of 4,744,641 bp (chromosome) and 40,955 bp (plasmid) in size. Genome mining revealed the presence of nonribosomal peptide synthases, two CRISPR systems, the Xps type 2 secretion system, and the Hrp type 3 secretion system. Surprisingly, this strain encodes an additional type 2 secretion system and a novel type 3 secretion system with enigmatic function, hitherto undescribed for xanthomonads. Four type 3 effector genes were found on complete or partial transposons, suggesting a role of transposons in effector gene evolution and spread. This genome sequence fills an important gap to better understand the biology and evolution of the early-branching xanthomonads, also known as clade-1 xanthomonads.

Keywords: Xanthomonas theicola; bacterial canker; bacterial pathogens; effector-encoding transposon; evolution; genomics; host parasite interactions; microbe-genome sequencing; pathogen effectors; tea plant; type 2 secretion; type 3 secretion.

MeSH terms

  • Genome, Bacterial* / genetics
  • Phylogeny
  • Plant Diseases
  • Tea
  • Xanthomonas* / genetics

Substances

  • Tea

Supplementary concepts

  • Xanthomonas theicola