Can easy chemistry produce complex, diverse, and novel molecules?

Drug Discov Today. 2020 Dec;25(12):2174-2181. doi: 10.1016/j.drudis.2020.09.027. Epub 2020 Oct 1.

Abstract

Easy-to-make compounds are often perceived to be inferior compared with molecules obtained through elaborate reaction schemes. This study evaluates in depths whether this perception is true.

MeSH terms

  • Drug Discovery*
  • Pharmaceutical Preparations / chemistry

Substances

  • Pharmaceutical Preparations