Whole-genome sequencing reveals potent therapeutic strategy for monomorphic epitheliotropic intestinal T-cell lymphoma

Blood Adv. 2020 Oct 13;4(19):4769-4774. doi: 10.1182/bloodadvances.2020001782.

Abstract

  1. Whole genomic and transcriptomic analyses of MEITL revealed multiple potential therapeutic targets.

  2. Synergistic effects of pimozide and romidepsin are shown in a well-characterized MEITL PDX model.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Humans
  • Lymphoma, T-Cell*