Planning Framework for Robot-assisted Blood-Brain Barrier Opening with Focused Ultrasound

Gaelle Thomas; Laurent Barbe; Benoit Larrat; Pauline Agou; Jonathan Vappou; Florent Nageotte

doi:10.1109/EMBC44109.2020.9175849

Planning Framework for Robot-assisted Blood-Brain Barrier Opening with Focused Ultrasound

Annu Int Conf IEEE Eng Med Biol Soc. 2020 Jul:2020:5033-5036. doi: 10.1109/EMBC44109.2020.9175849.

Authors

Gaelle Thomas, Laurent Barbe, Benoit Larrat, Pauline Agou, Jonathan Vappou, Florent Nageotte

PMID: 33019117
DOI: 10.1109/EMBC44109.2020.9175849

Abstract

This article presents a method to plan BloodBrain Barrier (BBB) disruption with Focused Ultrasound, under neuronavigated robotic assistance. Robotic and acoustic constraints are defined to estimate brain target accessibility. The relevance of the proposed framework is illustrated in specific brain target examples.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Biological Transport
Blood-Brain Barrier* / diagnostic imaging
Brain / diagnostic imaging
Robotics*
Ultrasonography