Pulmonary Complications in Candidates for Liver Transplantation

Middle East J Dig Dis. 2020 Jul;12(3):145-153. doi: 10.34172/mejdd.2020.176.

Abstract

The liver plays a pivotal role in maintaining the homeostasis of various organ systems. Also, end-stage liver disease and its complications are major causes of morbidity and mortality among adults. Individuals who develop a chronic liver disease are at increased risk of progression to multi-organ dysfunction, including the pulmonary system. The clinical complications of pulmonary problems related to the presence of liver disease range from mild (such as hypoxemia) to life-threatening diseases (such as portopulmonary hypertension and hepatopulmonary syndrome). Herein, the major pulmonary complications related to liver cirrhosis and considerations for performing liver transplantation are reviewed.

Keywords: Cirrhosis; Hepatopulmonary syndrome; Hypoxemia; Liver transplantation; Lung diseases; Portopulmonary hypertension.

Publication types

  • Review