Successfully treated bilateral renal fungal balls with continuous Anidulafulgin irrigation

N A M van Merode; J J Pat; M J H M Wolfhagen; G A Dijkstra

doi:10.1016/j.eucr.2020.101468

Successfully treated bilateral renal fungal balls with continuous Anidulafulgin irrigation

Urol Case Rep. 2020 Oct 26:34:101468. doi: 10.1016/j.eucr.2020.101468. eCollection 2021 Jan.

Authors

N A M van Merode¹, J J Pat¹, M J H M Wolfhagen², G A Dijkstra¹

Affiliations

¹ Department of Urology, Isala klinieken, Zwolle, the Netherlands.
² Laboratory of Clinical Microbiology and Infectious Diseases, Isala klinieken, Zwolle, the Netherlands.

Abstract

A 73-year-old man with a history of type 2 diabetes mellitus, nephrolithiasis, and recurrent urinary tract infections caused by Candida glabrata was admitted to our hospital. Urosepsis was diagnosed and C. glabrata was isolated from urine and blood cultures. Computed tomography intravenous pyelography (CT-IVP) revealed bilateral filling defects caused by renal fungal balls. Treatment initially comprised intravenous anidulafungin coupled with continuous local anidulafungin irrigation via bilateral nephrostomy tubes, which was followed by high-dose oral fluconazole. This regimen successfully eradicated the C. glabrata in follow-up cultures.

Keywords: Anidulafungin; Candida glabrata; Candidemia; Invasive candidiasis; Percutaneous nephrostomy.

Publication types

Case Reports