Cutaneous reactions to pediatric cancer treatment: Part I. Conventional chemotherapy

Dana Sous; Amy E Armstrong; Jennifer T Huang; Sonal Shah; Valerie M Carlberg; Carrie C Coughlin

doi:10.1111/pde.14418

Cutaneous reactions to pediatric cancer treatment: Part I. Conventional chemotherapy

Pediatr Dermatol. 2021 Jan;38(1):8-17. doi: 10.1111/pde.14418. Epub 2020 Nov 10.

Authors

Dana Sous¹, Amy E Armstrong^{2

3}, Jennifer T Huang⁴, Sonal Shah⁵, Valerie M Carlberg⁶, Carrie C Coughlin^{3

7}

Affiliations

¹ Washington University School of Medicine in St. Louis, St. Louis, MO, USA.
² Division of Pediatric Oncology, Department of Pediatrics, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.
³ St. Louis Children's Hospital, St. Louis, MO, USA.
⁴ Dermatology Program, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA.
⁵ Department of Dermatology, University of California, San Francisco, CA, USA.
⁶ Department of Dermatology, Medical College of Wisconsin, Milwaukee, WI, USA.
⁷ Division of Dermatology, Departments of Medicine and Pediatrics, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.

PMID: 33170534
DOI: 10.1111/pde.14418

Abstract

Chemotherapies often cause side effects of the skin, nails, and mucosal surfaces. These mucocutaneous toxicities contribute to morbidity and affect quality of life. Identification and management of these drug-induced eruptions is vital to allow for continuation of essential therapies. This review demonstrates the wide range of chemotherapy-induced cutaneous toxicities in children and includes clues for diagnosis as well as tips for counseling and management.

Keywords: cancer; chemotherapy; cutaneous reaction; pediatric; skin.

Publication types

Review

MeSH terms

Antineoplastic Agents* / adverse effects
Child
Drug Eruptions* / diagnosis
Drug Eruptions* / etiology
Humans
Neoplasms* / drug therapy
Quality of Life
Skin Diseases* / chemically induced
Skin Diseases* / diagnosis

Substances

Antineoplastic Agents