Systemic lupus erythematosus associated with recurrent anti-NMDA receptor encephalitis during pregnancy

Arch Womens Ment Health. 2021 Jun;24(3):525-528. doi: 10.1007/s00737-020-01088-y. Epub 2020 Nov 10.

Abstract

Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is caused by autoantibodies against the NR1 subunit of NMDAR. Recurrent cases combined with systemic lupus erythematosus (SLE) during pregnancy have not been reported. We report the case of a 23-year-old woman with a past history of SLE who presented with the characteristic features of anti-NMDAR encephalitis during both of her two pregnancies.

Keywords: Anti-N-methyl-D-aspartate receptor encephalitis; Pregnancy; Relapse; Systemic lupus erythematosus (SLE).

Publication types

  • Case Reports

MeSH terms

  • Anti-N-Methyl-D-Aspartate Receptor Encephalitis* / complications
  • Anti-N-Methyl-D-Aspartate Receptor Encephalitis* / diagnosis
  • Autoantibodies
  • Female
  • Humans
  • Lupus Erythematosus, Systemic* / complications
  • Lupus Erythematosus, Systemic* / diagnosis
  • Pregnancy
  • Pregnancy Complications / diagnosis*
  • Receptors, N-Methyl-D-Aspartate
  • Young Adult

Substances

  • Autoantibodies
  • Receptors, N-Methyl-D-Aspartate