Abstract
Introduction:
The intra-arterial chemotherapy (IAC) is increasingly used as a first-line therapy for retinoblastoma. The IAC has proved to be relatively safe. However, many local side effects of IAC have been described.
Case presentation:
This case report describes a local side effect presenting as proptosis and myositis with vascular access difficulty of the middle meningeal artery, in a 2-year-old male with left eye diffuse multifocal stage Vb retinoblastoma complicated with retinal detachment.
Discussion/conclusion:
IAC is assured to provide as efficient results in eliminating the tumor as the systemic chemotherapy, without causing the systemic side effects. It has become an alternative to systemic chemotherapy. A better understanding of the local side effects is required.
Keywords:
13q deletion syndrome; Intra-arterial chemotherapy; Local complication; Retinoblastoma.
© 2020 S. Karger AG, Basel.
MeSH terms
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Antineoplastic Combined Chemotherapy Protocols / administration & dosage
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Antineoplastic Combined Chemotherapy Protocols / adverse effects*
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Child, Preschool
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Chromosome Deletion
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Chromosome Disorders / complications
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Chromosome Disorders / diagnostic imaging
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Chromosome Disorders / drug therapy*
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Chromosomes, Human, Pair 13
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Exophthalmos / chemically induced
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Exophthalmos / diagnostic imaging
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Humans
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Injections, Intra-Arterial / adverse effects*
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Injections, Intra-Arterial / methods
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Intravitreal Injections / methods
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Male
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Meningeal Arteries / diagnostic imaging
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Meningeal Arteries / drug effects
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Myositis / chemically induced
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Myositis / diagnostic imaging
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Orbital Diseases / chemically induced*
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Orbital Diseases / diagnostic imaging
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Retinal Neoplasms / complications
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Retinal Neoplasms / diagnostic imaging
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Retinal Neoplasms / drug therapy*
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Retinoblastoma / complications
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Retinoblastoma / diagnostic imaging
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Retinoblastoma / drug therapy*