The once and future gene therapy

Karen Bulaklak; Charles A Gersbach

doi:10.1038/s41467-020-19505-2

The once and future gene therapy

Nat Commun. 2020 Nov 16;11(1):5820. doi: 10.1038/s41467-020-19505-2.

Authors

Karen Bulaklak^{1

2}, Charles A Gersbach^{3

4

5

6}

Affiliations

¹ Department of Biomedical Engineering, Duke University, Durham, NC, USA.
² Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA.
³ Department of Biomedical Engineering, Duke University, Durham, NC, USA. charles.gersbach@duke.edu.
⁴ Center for Advanced Genomic Technologies, Duke University, Durham, NC, USA. charles.gersbach@duke.edu.
⁵ Department of Surgery, Duke University, Durham, NC, USA. charles.gersbach@duke.edu.
⁶ Department of Cell Biology, Duke University, Durham, NC, USA. charles.gersbach@duke.edu.

Abstract

Gene therapy is at an inflection point. Recent successes in genetic medicine have paved the path for a broader second wave of therapies and laid the foundation for next-generation technologies. This comment summarizes recent advances and expectations for the near future.

Publication types

Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

MeSH terms

Animals
Clinical Trials as Topic
Disease / genetics
Gene Editing
Genetic Therapy*
Humans

Abstract

Publication types

MeSH terms

Grants and funding