Arterial Delivery of VEGF-C Stabilizes Atherosclerotic Lesions

Circ Res. 2021 Jan 22;128(2):284-286. doi: 10.1161/CIRCRESAHA.120.317186. Epub 2020 Nov 19.
No abstract available

Keywords: atherosclerosis; cytokine; fibronectin; inflammation; leukocyte.

Publication types

  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Antibodies, Monoclonal, Humanized / pharmacology*
  • Atherosclerosis / drug therapy*
  • Atherosclerosis / metabolism
  • Atherosclerosis / pathology
  • Cells, Cultured
  • Cholesterol / metabolism
  • Collagen / metabolism
  • Disease Models, Animal
  • Endoplasmic Reticulum Stress / drug effects
  • Humans
  • Immunoconjugates / pharmacology*
  • Mice
  • Mice, Knockout, ApoE
  • Muscle, Smooth, Vascular / drug effects*
  • Muscle, Smooth, Vascular / metabolism
  • Muscle, Smooth, Vascular / pathology
  • Myocytes, Smooth Muscle / drug effects*
  • Myocytes, Smooth Muscle / metabolism
  • Myocytes, Smooth Muscle / pathology
  • Necrosis
  • Plaque, Atherosclerotic*
  • Vascular Endothelial Growth Factor C / pharmacology*

Substances

  • Antibodies, Monoclonal, Humanized
  • F8 monoclonal antibody
  • Immunoconjugates
  • Vascular Endothelial Growth Factor C
  • Collagen
  • Cholesterol