Systemic Cat-Scratch Disease: a "Troublesome" Diagnosis

Pediatr Infect Dis J. 2021 Mar 1;40(3):e117-e119. doi: 10.1097/INF.0000000000002996.

Abstract

Diagnosis of systemic cat scratch disease may be challenging. Here, we describe a case of an immunocompetent girl exhibiting fever and multifocal hepatosplenic abscesses. Diagnostic tests for Bartonella henselae infection (enzyme immunoassay and polymerase chain reaction) were found steadily negative and the diagnosis, suspected on the basis of the Margilet's criteria, was finally confirmed by indirect immunofluorescent antibodies.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Anti-Bacterial Agents / administration & dosage
  • Anti-Bacterial Agents / therapeutic use
  • Azithromycin / administration & dosage
  • Azithromycin / therapeutic use
  • Bartonella henselae / immunology*
  • Bartonella henselae / isolation & purification
  • Cat-Scratch Disease / blood
  • Cat-Scratch Disease / diagnosis*
  • Cat-Scratch Disease / drug therapy
  • Doxycycline / administration & dosage
  • Doxycycline / therapeutic use
  • Drug Therapy, Combination
  • Female
  • Fever / diagnosis
  • Fluorescent Antibody Technique / methods
  • Humans
  • Serologic Tests

Substances

  • Anti-Bacterial Agents
  • Azithromycin
  • Doxycycline