Human iPSC-Derived Cardiomyocytes of Peripartum Patients With Cardiomyopathy Reveal Aberrant Regulation of Lipid Metabolism

Circulation. 2020 Dec 8;142(23):2288-2291. doi: 10.1161/CIRCULATIONAHA.119.044962. Epub 2020 Dec 7.

Affiliations

¹ Department of Cardiology (M.F.H., N.B., K.F.A.G., P.v.d.M.), University Medical Center Groningen, University of Groningen, The Netherlands.
² Department of Cardiology and Angiology, Hannover Medical School, Germany (M.R.-H., S.P., D.H.-K.).
³ European Research Institute for the Biology of Aging (T.V.d.J.), University Medical Center Groningen, University of Groningen, The Netherlands.

^# Contributed equally.

No abstract available

Keywords: cardiomyopathies; heart failure; metabolic networks and pathways; peripartum period; pregnancy; sequence analysis, RNA.

Publication types

Case Reports
Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Cardiomyopathies / diagnostic imaging
Cardiomyopathies / metabolism*
Female
Humans
Induced Pluripotent Stem Cells / metabolism*
Lipid Metabolism / physiology*
Myocytes, Cardiac / metabolism*
Peripartum Period / metabolism*
Pregnancy
Pregnancy Complications, Cardiovascular / diagnostic imaging
Pregnancy Complications, Cardiovascular / metabolism*