Phase 1b study of tirabrutinib in combination with idelalisib or entospletinib in previously treated B-cell lymphoma

Leukemia. 2021 Jul;35(7):2108-2113. doi: 10.1038/s41375-020-01108-x. Epub 2020 Dec 17.
No abstract available

Publication types

  • Clinical Trial, Phase I
  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Antineoplastic Agents / therapeutic use*
  • Female
  • Humans
  • Imidazoles / therapeutic use*
  • Indazoles / therapeutic use*
  • Lymphoma, B-Cell / drug therapy*
  • Male
  • Middle Aged
  • Protein Kinase Inhibitors / therapeutic use*
  • Purines / therapeutic use*
  • Pyrazines / therapeutic use*
  • Pyrimidines / therapeutic use*
  • Quinazolinones / therapeutic use*

Substances

  • 6-(1H-indazol-6-yl)-N-(4-morpholinophenyl)imidazo(1,2-a)pyrazin-8-amine
  • Antineoplastic Agents
  • Imidazoles
  • Indazoles
  • Protein Kinase Inhibitors
  • Purines
  • Pyrazines
  • Pyrimidines
  • Quinazolinones
  • tirabrutinib
  • idelalisib