Cardiovascular disease (CVD) has been an important public health issue in China. Recently, the prevalence of obesity, elevated blood pressure, hyperglycemia, dyslipidemia, and unhealthy lifestyles was high in Chinese children and adolescents, which might increase the risk of short-term target organ damage and adult CVD. Therefore, we selected one primary school in Huantai County, Zibo City between November 2017 and January 2018 to establish the Huantai Childhood Cardiovascular Health Cohort Study. The aim of this project was to investigate the effects of childhood exposures on short-term target organ damage and adult CVD, and to provide evidence to curb the epidemic of CVD in China from the source. A total of 1 515 children aged 6-11 years old were included at the baseline. In this paper, we will introduce the overall design of the survey, including participants, methods, quality control, basic characteristics of the participants, study limitations, and future directions, which might provide some useful implications for similar researches in the future.
心血管疾病已成为影响我国居民健康的重大公共卫生问题。近年来，我国儿童青少年肥胖、血压偏高、高血糖、血脂异常以及不健康生活方式等呈现流行态势，这可能会增加近期靶器官损害和成年期心血管疾病的发生风险。因此，本课题组于2017年11月—2018年1月以山东省淄博市桓台县一所公立小学为基础建立了包括1 515名6~11岁儿童的“桓台儿童心血管健康随访队列”，旨在探讨儿童期各种暴露因素对近期靶器官损害以及成年期心血管疾病的影响，为从源头上遏制我国心血管疾病的流行提供循证依据。本研究将主要介绍该项目的调查对象、调查内容、质量控制、基线特征、研究局限性以及未来展望等，以期为其他相关研究提供参考。.
Keywords: Cardiovascular disease; Child; Cohort studies.