STAT3 and STAT5B mutations have unique distribution in T-cell large granular lymphocyte proliferations and advanced myeloid neoplasms

Shiqiang Qu; Yujiao Jia; Huijun Wang; Xiaofei Ai; Zefeng Xu; Tiejun Qin; Lijuan Pan; Bing Li; Gang Huang; Robert Peter Gale; Zhijian Xiao

doi:10.1080/10428194.2020.1869964

STAT3 and STAT5B mutations have unique distribution in T-cell large granular lymphocyte proliferations and advanced myeloid neoplasms

Leuk Lymphoma. 2021 Jun;62(6):1506-1509. doi: 10.1080/10428194.2020.1869964. Epub 2021 Jan 7.

Authors

Shiqiang Qu^{1

2

3}, Yujiao Jia^{2

4}, Huijun Wang^{2

4}, Xiaofei Ai^{2

4}, Zefeng Xu^{1

2

3}, Tiejun Qin^{1

2}, Lijuan Pan^{1

2}, Bing Li^{1

2

3}, Gang Huang⁵, Robert Peter Gale⁶, Zhijian Xiao^{1

2

3}

Affiliations

¹ MDS and MPN Center, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China.
² National Clinical Research Centre for Blood Diseases, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China.
³ State key Laboratory of Experimental Hematology, National Clinical Research Center for Blood Disease, Institute of Hematology & Blood Disease Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin, China.
⁴ Hematologic Pathology Centre, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China.
⁵ Divisions of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
⁶ Haematology Research Centre, Department of Immunology and Inflammation, Imperial College London, London, United Kingdom.

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Humans
Leukemia, Large Granular Lymphocytic* / diagnosis
Leukemia, Large Granular Lymphocytic* / genetics
Mutation
Neoplasms*
STAT3 Transcription Factor / genetics
STAT3 Transcription Factor / metabolism
STAT5 Transcription Factor / genetics
STAT5 Transcription Factor / metabolism
T-Lymphocytes / metabolism

Substances

STAT3 Transcription Factor
STAT3 protein, human
STAT5 Transcription Factor
STAT5B protein, human

Publication types

MeSH terms

Substances

Grants and funding