SARS-CoV-2 placentitis: An uncommon complication of maternal COVID-19

Placenta. 2021 Jan 15:104:261-266. doi: 10.1016/j.placenta.2021.01.012. Epub 2021 Jan 11.

Abstract

We present a case of third trimester pregnancy complicated by SARS-CoV-2 infection and subsequent reduced fetal movements, resulting in emergency Caesarean delivery with demonstrable placental SARS-CoV-2 placentitis. We show through illustration of this case and literature review that SARS-Co-V-2 placentitis is an uncommon but readily recognisable complication of maternal SARS-CoV-2 infection that may be a marker of potential vertical transmission and that may have the capacity to cause fetal compromise through a direct injurious effect on the placenta.

Keywords: Histiocytic intervillositis; Placental pathology; Placentitis; SARS-CoV-2; Vertical transmission.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • COVID-19 / complications*
  • COVID-19 / pathology
  • Female
  • Humans
  • Placenta / pathology*
  • Placenta Diseases / pathology
  • Placenta Diseases / virology*
  • Pregnancy
  • Pregnancy Complications, Infectious / pathology
  • Pregnancy Complications, Infectious / virology*
  • Pregnancy Trimester, Third
  • SARS-CoV-2