Thrombocytosis with acquired von Willebrand disease in an adolescent with sickle cell disease

Abstract

Thrombocytosis is common in sickle cell disease and may contribute to vaso-occlusion. Hydroxyurea treats extreme thrombocytosis. Acquired von Willebrand disease should be considered prior to aspirin therapy.

Keywords: acquired Von Willebrand disease; priapism; sickle cell disease; thrombocytosis.