Pulmonary Hypertension in Pregnancy

Clin Chest Med. 2021 Mar;42(1):91-99. doi: 10.1016/j.ccm.2020.10.006. Epub 2021 Jan 9.

Abstract

Pregnancy in pulmonary hypertension (PH) is associated with a high maternal morbidity and mortality. The normal physiologic pulmonary and systemic hemodynamic alterations that occur during pregnancy are poorly tolerated during pregnancy, birth, and the immediate postpartum period. This article (a) highlights the normal anatomic and physiologic changes that accompany pregnancy and the potential deleterious consequences on the cardiopulmonary circulation in pregnant PH patients and (b) provides an in-depth approach in the management of the pregnant PH patient.

Keywords: PAH; Physiologic changes of pregnancy; Pregnancy; Pregnancy management; Pulmonary hypertension.

Publication types

  • Review

MeSH terms

  • Female
  • Hemodynamics*
  • Humans
  • Hypertension, Pulmonary* / physiopathology
  • Hypertension, Pulmonary* / therapy
  • Pregnancy
  • Pregnancy Complications, Cardiovascular* / physiopathology
  • Pregnancy Complications, Cardiovascular* / therapy