Heterogeneity in Metastatic Potential of Cancer Cells Is Revealed En Masse

Pavitra Viswanath; Alana L Welm

doi:10.1016/j.ccell.2021.01.017

Heterogeneity in Metastatic Potential of Cancer Cells Is Revealed En Masse

Cancer Cell. 2021 Feb 8;39(2):148-150. doi: 10.1016/j.ccell.2021.01.017.

Authors

Pavitra Viswanath¹, Alana L Welm²

Affiliations

¹ Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA.
² Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA. Electronic address: alana.welm@hci.utah.edu.

PMID: 33561396
DOI: 10.1016/j.ccell.2021.01.017

Abstract

A new study in Nature determines metastatic tropism in xenograft mouse models. This results in a metastasis map for 21 tumor types, the utility of which is demonstrated by identifying lipid metabolism to be uniquely altered in breast cancer cell lines that metastasize to the brain.

Publication types

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MeSH terms

Animals
Cell Line, Tumor
Disease Models, Animal
Mice
Neoplasms*