Research Advance on Qingfei Paidu Decoction in Prescription Principle, Mechanism Analysis and Clinical Application

Wei Ren; Yue Ma; Raoqiong Wang; Pan Liang; Qin Sun; Qingrong Pu; Li Dong; Maryam Mazhar; Gang Luo; Sijin Yang

doi:10.3389/fphar.2020.589714

Research Advance on Qingfei Paidu Decoction in Prescription Principle, Mechanism Analysis and Clinical Application

Front Pharmacol. 2021 Jan 27:11:589714. doi: 10.3389/fphar.2020.589714. eCollection 2020.

Authors

Wei Ren^{1

2}, Yue Ma¹, Raoqiong Wang¹, Pan Liang¹, Qin Sun^{1

2}, Qingrong Pu¹, Li Dong¹, Maryam Mazhar^{1

2}, Gang Luo¹, Sijin Yang^{1

2}

Affiliations

¹ National Traditional Chinese Medicine Clinical Research Base, Affiliated Traditional Chinese Medicine Hospital, Southwest Medical University, Luzhou, China.
² Faculty of Integrative Medicine, Southwest Medical University, Luzhou, China.

Abstract

Since the sudden epidemic of coronavirus disease 2019 (COVID-19), the State Administration of Traditional Chinese Medicine immediately organized experts to formulate and screen the effective prescriptions of traditional Chinese medicine according to the characteristics of the novel coronavirus infection. Qingfei Paidu decoction (QFPDD) has been proven to be effective in multi-provincial clinical trials, and has been selected as a general prescription for the treatment of COVID-19 in different stages that was later promoted to be used nationwide. This review highlights the latest advances of QFPDD, focusing on the TCM theory, mechanism analysis, clinical application of QFPDD and its future perspectives. Moreover, an in-depth discussion of some valuable issues and possible development for future research on QFPDD is also discussed, aiming to provide a novel guide to combat the global epidemic COVID-19.

Keywords: clinical application; mechanism analysis; novel coronavirus pneumonia; prescription principle; qingfei paidu decoction.

Publication types

Review