(Ex-)breast cancer patients with (pre-existing) symptoms of anxiety and/or depression experience higher barriers to contact health care providers during the COVID-19 pandemic

Breast Cancer Res Treat. 2021 Apr;186(2):577-583. doi: 10.1007/s10549-021-06112-y. Epub 2021 Feb 18.

Abstract

Purpose: To identify factors associated with (perceived) access to health care among (ex-)breast cancer patients during the COVID-19 pandemic.

Methods: Cross-sectional study within a large prospective, multicenter cohort of (ex-)breast cancer patients, i.e., UMBRELLA. All participants enrolled in the UMBRELLA cohort between October 2013 and April 2020 were sent a COVID-19-specific survey, including the Hospital Anxiety and Depression Scale (HADS) questionnaire.

Results: In total, 1051 (66.0%) participants completed the survey. During COVID-19, 284 (27.0%) participants reported clinically relevant increased levels of anxiety and/or depression, i.e., total HADS score ≥ 12. Participants with anxiety and/or depression reported statistically significant higher barriers to contact their general practitioner (47.5% vs. 25.0%, resp.) and breast cancer physicians (26.8% vs. 11.2%, resp.) compared to participants without these symptoms. In addition, a higher proportion of participants with anxiety and/or depression reported that their current treatment or (after)care was affected by COVID-19 compared to those without these symptoms (32.7% vs. 20.5%, resp.). Factors independently associated with symptoms of anxiety and/or depression during COVID-19 were pre-existent anxiety (OR 6.1, 95% CI 4.1-9.2) or depression (OR 6.0, 95% CI 3.5-10.2).

Conclusion: During the COVID-19 pandemic, (ex-)breast cancer patients with symptoms of anxiety and/or depression experience higher barriers to contact health care providers. Also, they more often report that their health care was affected by COVID-19. Risk factors for anxiety and/or depression during COVID-19 are pre-existent symptoms of anxiety or depression. Extra attention-including mental health support-is needed for this group.

Keywords: Anxiety; Breast cancer; COVID-19; Depression; Patient-reported outcomes; UMBRELLA.

Publication types

  • Multicenter Study
  • Observational Study

MeSH terms

  • Aged
  • Anxiety / epidemiology
  • Anxiety / psychology*
  • Breast Neoplasms / epidemiology
  • Breast Neoplasms / psychology*
  • COVID-19 / epidemiology
  • COVID-19 / psychology*
  • Cancer Survivors / psychology*
  • Cancer Survivors / statistics & numerical data
  • Cross-Sectional Studies
  • Depression / epidemiology
  • Depression / psychology*
  • Female
  • Humans
  • Middle Aged
  • Patient Acceptance of Health Care / psychology
  • Patient Acceptance of Health Care / statistics & numerical data
  • Prevalence
  • Prospective Studies
  • Risk Factors
  • SARS-CoV-2
  • Surveys and Questionnaires