Psychological peritraumatic risk factors for post-traumatic stress disorder in children and adolescents: A meta-analytic review

Jessica Memarzia; Jack Walker; Richard Meiser-Stedman

doi:10.1016/j.jad.2021.01.016

Psychological peritraumatic risk factors for post-traumatic stress disorder in children and adolescents: A meta-analytic review

J Affect Disord. 2021 Mar 1:282:1036-1047. doi: 10.1016/j.jad.2021.01.016. Epub 2021 Jan 11.

Authors

Jessica Memarzia¹, Jack Walker², Richard Meiser-Stedman³

Affiliations

¹ Peterborough Integrated Neurodevelopmental Service, Child and Adolescent Mental Health Service, Cambridgeshire and Peterborough Foundation NHS Trust, Winchester Place, 80 Thorpe Road, Peterborough, PE3 6AP, Canada; Department of Clinical Psychology and Psychological Therapies, Norwich Medical School, University of East Anglia, NR4 7TJ.
² Department of Clinical Psychology and Psychological Therapies, Norwich Medical School, University of East Anglia, NR4 7TJ.
³ Department of Clinical Psychology and Psychological Therapies, Norwich Medical School, University of East Anglia, NR4 7TJ. Electronic address: r.meiser-stedman@uea.ac.uk.

PMID: 33601676
DOI: 10.1016/j.jad.2021.01.016

Abstract

Background: Meta-analytic reviews concerning predictors of PTSD in children and adolescents have predominantly identified evidence relating to pre- and post-trauma risk factors; however, there is little evidence regarding peritraumatic risk factors. This paper comprised a systematic review and meta-analysis of studies exploring psychological peritraumatic risk factors for PTSD in youth.

Methods: Thirty-two studies were identified. Random effects meta-analyses were undertaken, with meta-regressions to explore the moderating role of study characteristics (gender, sex, timing of assessment after trauma, study quality, design and trauma type) on the size of effect of predictive factors.

Results: Peritraumatic subjective threat (k = 28; r = 0.37, 95% CI=0.31-0.42) yielded a medium effect size estimate, while dissociation (k = 5; r = 0.17, 95% CI=0.03-0.29) and data-driven processing (feeling muddled or confused during the trauma) (k = 2; r = 0.29, 95% CI=0.14-0.43) yielded smaller population effect size estimates for the relationship with PTSD symptoms. Perceived life threat yielded a medium sized effect (k = 12; r = 0.37, 95% CI=0.32-0.41). The relationship between subjective threat and PTSD symptoms was moderated by the percentage of female participants. Estimates of heterogeneity were high in studies assessing perceived threat and fear (I² = 95%), but moderate and low within studies assessing dissociation and data-driven processing (I² = 57% and 0%, respectively).

Limitations: Peritraumatic psychological processes were commonly assessed using single-item measures. Studies primarily concerned single-incident traumas, limiting generalisability.

Conclusions: Peritraumatic experiences, particularly relating to subjective threat, are important correlates of subsequent PTSD, which implicates timely assessment of these experiences in youth to inform identification of at-risk groups and implementation and design of intervention.

Keywords: Adolescents; Children; Meta-analysis; PTSD; Peritraumatic; Risk factors.

Publication types

Meta-Analysis
Review
Systematic Review

MeSH terms

Adolescent
Child
Dissociative Disorders
Emotions
Female
Humans
Risk Factors
Stress Disorders, Post-Traumatic*