Risk factors for enterococcal urinary tract infections: a multinational, retrospective cohort study

Eur J Clin Microbiol Infect Dis. 2021 Sep;40(9):2005-2010. doi: 10.1007/s10096-021-04207-4. Epub 2021 Mar 2.

Abstract

Complicated urinary tract infection (cUTI) is a frequent cause of morbidity. In this multinational retrospective cohort study, we aimed to demonstrate risk factors for enterococcal UTI. Univariate and multivariate analyses of risk factors for enterococcal infection were performed. Among 791 hospitalized patients with cUTI, enterococci accounted for approximately 10% of cases (78/791). Risk factors for enterococcal UTI in multivariable analysis were male gender, age range of 55-75 years, catheter-associated UTI, and urinary retention. This information may assist treating physicians in their decision-making on prescribing empiric anti-enterococcus treatment to hospitalized patients presenting with cUTI and thus improve clinical outcomes.

Keywords: Antibiotic stewardship; Complicated urinary tract infection (UTI); Enterococcus; Risk factors.

Publication types

  • Multicenter Study
  • Observational Study

MeSH terms

  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Enterococcus / drug effects
  • Enterococcus / pathogenicity*
  • Europe
  • Female
  • Hospitalization / statistics & numerical data
  • Humans
  • Internationality
  • Male
  • Middle Aged
  • Middle East
  • Retrospective Studies
  • Risk Factors
  • Urinary Tract Infections / complications
  • Urinary Tract Infections / drug therapy
  • Urinary Tract Infections / microbiology*

Substances

  • Anti-Bacterial Agents