Preventing Recurrent Preeclampsia by Tailored Treatment of Nonphysiologic Hemodynamic Adjustments to Pregnancy

Hypertension. 2021 Jun;77(6):2045-2053. doi: 10.1161/HYPERTENSIONAHA.120.16502. Epub 2021 Apr 5.

Eva G Mulder^{1

2}, Chahinda Ghossein-Doha^{2

3

4}, Ella Cauffman¹, Veronica A Lopes van Balen^{1

2}, Veronique M M M Schiffer^{1

2}, Robert-Jan Alers^{1

2}, Jolien Oben³, Luc Smits⁵, Sander M J van Kuijk⁶, Marc E A Spaanderman¹

¹ Department of Obstetrics and Gynecology (E.G.M., E.C., V.A.L.v.B., V.M.M.M.S., R.J.A., M.E.A.S.), Maastricht University Medical Centre, the Netherlands.
² GROW School for Oncology and Developmental Biology (E.G.M., C.G.D., V.A.L.v.B., V.M.M.M.S., R.J.A.), Maastricht University Medical Centre, the Netherlands.
³ Department of Cardiology (C.G.D., J.O.), Maastricht University Medical Centre, the Netherlands.
⁴ Cardiovascular Research Institute Maastricht (C.G.D.), Maastricht University Medical Centre, the Netherlands.
⁵ Department of Epidemiology (L.S.), Maastricht University Medical Centre, the Netherlands.
⁶ Department of Clinical Epidemiology and Medical Technology Assessment (S.M.J.v.K.), Maastricht University Medical Centre, the Netherlands.

Abstract

[Figure: see text].

Trial registration: ClinicalTrials.gov NCT04216706.

Keywords: hemodynamics; hypertension; physiology; preeclampsia; pregnancy.