The clinicopathological analysis of organising pneumonia in myelodysplastic syndrome: high frequency in der(1;7)(q10; p10)

Manabu Matsunawa; Yasuyuki Inoue; Kunihiro Yagihashi; Yoshio Aida; Akiko Uchida; Yu Uemura; Yusuke Saiki; Madoka Takimoto; Fumiaki Sano; Ikuo Miura; Ayako Arai

doi:10.1111/bjh.17473

The clinicopathological analysis of organising pneumonia in myelodysplastic syndrome: high frequency in der(1;7)(q10; p10)

Br J Haematol. 2021 Jul;194(1):214-217. doi: 10.1111/bjh.17473. Epub 2021 Apr 14.

Authors

Manabu Matsunawa¹, Yasuyuki Inoue¹, Kunihiro Yagihashi², Yoshio Aida³, Akiko Uchida⁴, Yu Uemura⁴, Yusuke Saiki⁴, Madoka Takimoto¹, Fumiaki Sano¹, Ikuo Miura⁴, Ayako Arai^{4

5}

Affiliations

¹ Department of Internal Medicine, Division of Hematology, Yokohama City Seibu Hospital, St. Marianna University School of Medicine, Yokohama, Japan.
² Department of Radiology, Kawasaki Municipal Tama Hospital, Kawasaki, Japan.
³ Department of Pathology, Yokohama City Seibu Hospital, St. Marianna University School of Medicine, Yokohama, Japan.
⁴ Division of Hematology and Oncology, Department of Internal Medicine, St. Marianna University School of Medicine, Kawasaki, Japan.
⁵ Department of Hematological Therapeutics, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.

PMID: 33855707
DOI: 10.1111/bjh.17473

No abstract available

Keywords: In conclusion a relationship between OP and der(1;7)(q10; p10) was suggested in MDS. Further study based on a larger number of cases is needed to confirm the validity of our hypothesis and to unravel the mutation’s pathogenesis as well as the impact on clinical features of MDS.; der(1;7)(q10; p10); myelodysplastic syndrome; organizing pneumonia; prednisolone.

Publication types

Letter

MeSH terms

Aged
Chromosome Aberrations*
Chromosomes, Human, Pair 1 / ultrastructure*
Chromosomes, Human, Pair 7 / ultrastructure*
Cryptogenic Organizing Pneumonia / diagnostic imaging
Cryptogenic Organizing Pneumonia / drug therapy
Cryptogenic Organizing Pneumonia / etiology*
Cryptogenic Organizing Pneumonia / genetics
Female
Hematopoietic Stem Cell Transplantation
Humans
Male
Myelodysplastic Syndromes / complications*
Myelodysplastic Syndromes / genetics
Myelodysplastic Syndromes / pathology
Myelodysplastic Syndromes / therapy
Prednisolone / therapeutic use
Retrospective Studies

Substances

Prednisolone